The Covid-19 products provided by Keynovo Biotech mainly include active pharmaceutical ingredients, intermediates and excipients. The main products are chloroquine phosphate (CAS 50-63-5), hydroxychloroquine (CAS 118-42-3), Sulfobutyl Ether-β-cyclodextrin (CAS 182410-00-0)
Hydroxychloroquine Sulfate is an antimalarial drug, which also has anti-inflammatory, immunomodulatory and anticoagulant effects. At present, hydroxychloroquine is clinically mainly used for the treatment of rheumatoid arthritis, juvenile chronic arthritis, discoid lupus erythematosus and systemic lupus erythematosus, but the clinical effect is slow and usually takes 2 to 4 months.
Chloroquine phosphate is a 4-aminoquinoline antimalarial drug, which can inhibit the nucleic acid synthesis of Plasmodium schizonts, interfere with the growth and reproduction of Plasmodium schizonts, and have a high-efficiency killing effect on Plasmodium schizonts in the red stage.
Sulfobutyl Ether Beta Cyclodextrin (CAS: 182410-00-0) is a new type of anionic, highly water-soluble cyclodextrin derivative. Can be used as an excipient for drugs to treat COVID-19.
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