Hyaluronic acid is also called sodium hyaluronate. It is also widely present in animals, so the earliest hyaluronic acid used is extracted from animals, especially from cockscombs. Because of the small amount, the price is very expensive, and the scope of application is limited to medical treatment.
Later, researchers used bioengineering to produce hyaluronic acid in factories, which reduced the price to a level that can be widely used and became the most classic and excellent moisturizing ingredient. Today, most skin care products add a little hyaluronic acid. .
Due to the good biocompatibility of hyaluronic acid, it is also made into injection fillers for micro plastic surgery, which can adjust facial contours, fill wrinkles and depressions, and improve skin shrinkage. The rise of mesotherapy, especially the dot matrix injection of microneedles (ie "water light needles"), has further expanded the use of hyaluronic acid in cosmetic dermatology.
However, in addition to the above uses in skin care and medical beauty, many things that may not be understood are:
Studies in the past 10 years have shown that oral hyaluronic acid can not only be absorbed by the body, but also improve skin quality.
In 2017, Japan's Mariko Oe et al. conducted a randomized controlled clinical study and believed that oral hyaluronic acid (including 2000D and 300,000D molecular weight) can reduce wrinkles and improve skin. The study recruited 60 Japanese men and women aged 22-59 years with crow's feet and randomly divided into two groups. They were given 2000D, or 300,000D hyaluronic acid, or placebo, at a dose of 120mg/day, continuous consumption of 12 week.
The results showed that the hyaluronic acid group was significantly comparable to the placebo group in terms of skin wrinkle volume ratio, wrinkle area ratio, and wrinkle volume. After 8 weeks, wrinkles in the 300,000 D hyaluronic acid group were significantly reduced compared to the placebo group. After 12 weeks, the skin brightness and skin softness of all groups were better than the initial level.
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