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Reduced and Oxidized Glutathione: Understanding the Differences Apr 21, 2023

Glutathione is an important antioxidant that can be converted into two forms: reduced glutathione and oxidized glutathione. These two forms play an important role in maintaining the stability and health of the body by repairing damaged cells and enhancing the antioxidant capacity of cells. Understanding the differences between reduced and oxidized glutathione is crucial for understanding how this antioxidant functions.


One key difference between reduced and oxidized glutathione is their molecular formulas. Reduced glutathione has a molecular formula of C10H17N3O6S and a molecular weight of 307.33, while oxidized glutathione has a molecular formula of C20H32N6O12S2 and a molecular weight of 612.63.


Another difference between the two forms of glutathione is their melting points. Reduced glutathione decomposes at a melting point of 189-193°C, while oxidized glutathione decomposes at a melting point of 178°C.


Reduced and oxidized glutathione also have different uses. Reduced glutathione has a certain curative effect on various liver diseases, especially on alcoholic liver disease and drug poisoning liver disease. It has anti-oxidation, integrated detoxification, and other functions and is used in medicines, nutraceuticals, health functional foods, food supplements, beauty cosmetics, etc. On the other hand, oxidized glutathione is used for scientific research, experiments, and enzymatic determination of hydrogen acceptors for NADP and NADPH.


In summary, reduced and oxidized glutathione are two forms of an important antioxidant that play crucial roles in maintaining the stability and health of the body. Understanding the differences between these two forms can help us better understand how this antioxidant functions.


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