Vitamin E Polyethylene Glycol Succinate TPGS Powder

TPGS stands for Tocopheryl Polyethylene Glycol 1000 Succinate. It is a water-soluble, nonionic vitamin E derivative. TPGS is derived from natural vitamin E and modified to improve its solubility in aqueous systems. It is commonly available in the form of yellow to light brown powder.

CAS #:
9002-96-4
Certificates:
GMP/Kosher/Halal/USDFM
Specifications:
USP/BP/EP
Payment:
L/C,T/T,D/P,Western Union,Paypal,Money Gram

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Product Detail

Description
TPGS stands for Tocopheryl Polyethylene Glycol 1000 Succinate. It is a water-soluble, nonionic vitamin E derivative. TPGS is derived from natural vitamin E and modified to improve its solubility in aqueous systems. It is commonly available in the form of yellow to light brown powder.

Function
TPGS has several important functions in various industries. Firstly, it acts as a solubilizer and emulsifier, helping to enhance the solubility and stability of poorly water-soluble drugs and nutraceuticals in aqueous environments. Secondly, TPGS exhibits excellent antioxidant properties, which can protect sensitive compounds from oxidation and degradation. Additionally, TPGS has been found to enhance drug absorption through various mechanisms, including inhibition of efflux transporters and improvement of mucosal permeability.

Application

Medicinal Field:
It is mainly used as excipient and absorption enhancer. Due to its emulsifying and solubilizing effects, it can effectively improve the bioavailability of drugs. Thus, it can reduce the amount of drug use and reduce the toxic side effects of drugs.
1. Anti-tumor drug: FDA approved paclitaxel emulsion formulation (Sonus Pharmaceuticals)
2. Anti-HIV drugs: Agenerase (Amprenavir) and APTIVUS (Telanavir).
3. Anti-hepatitis C virus (HCV) drugs: VIEKERA Pack tablets.
4. Ophthalmic medications: dry eye; prevention of contact lens wear; healing of the postoperative cornea.
5. Treatment of vitamin E deficiency caused by chronic bile deficiency.

Food and Cosmetics Field:

1. Converts a wide range of natural nutrients into stable, water-soluble liquids or powders.
2. Has antioxidant and anti-aging effects.

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Subject : Vitamin E Polyethylene Glycol Succinate TPGS Powder

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